Name | ARN 077(ARN077) |
Synonyms | URB913 ARN 077(ARN077) Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester |
CAS | 1373625-34-3 |
Molecular Formula | C16H21NO4 |
Molar Mass | 291.34 |
biological activity | ARN 077 is a potent and selective inhibitor of N-acetylethanolamine amidase (NAAA), it has an IC50 value of 7 nM for human NAAA. ARN 077 can significantly increase the level of palmitoyl ethanolamine (PEA) in the central nervous system, and has a wide range of analgesic activity in mice and rats. |
Target | IC50: 7 nM (human NAAA). |